Depakote dosage for schizophrenia

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Depakote tablets are administered orally. The recommended initial dose is 750 mg daily in divided doses. The dose should be increased as rapidly as possible to achieve the lowest therapeutic dose which produces the desired clinical effect or the desired range of plasma concentrations Depakote ER initial dose: 25 mg/kg PO once daily Increase as rapidly as possible to achieve the lowest therapeutic dose that provides desired clinical effect or plasma concentration Not to exceed.. This article takes a systematic look at the literature regarding the efficacy of using valproic acid (Depakote) as an adjunctive (additional to an antipsychotic) medication for schizophrenia. This medicine is a mood stabilizer and is typically a first line drug for treating bipolar disorder The dose usually ranges from 1000 mg to 3500 mg or more. Only your healthcare provider can determine the correct dose for you, as sometimes the dose required is based on your weight. Valproate tablets: Swallow whole. Do not crush, chew or split tablets

Schizophrenien - bei Amazon

  1. Background: Many people with schizophrenia do not achieve a satisfactory treatment response with ordinary antipsychotic drug treatment. In these cases, various add-on medications are used; valproate is one of these. Objectives: To review the effects of valproate for the treatment of schizophrenia and schizophrenia-like psychoses
  2. Valproate (the active moiety of both valproic acid and divalproex sodium) is commonly used as an adjunctive agent for the treatment of schizophrenia. Among the anticonvulsants, valproate is the most extensively studied in patients with schizophrenia. Theoretical underpinnings for valproate in schizo
  3. istered at an initial daily dose of 20 mg twice daily with food. For intramuscular dosing, the recommended dose of Depakote is 10 mg to 20 mg ad

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  1. e whether: 1. valproate alone is an effective treatment for schizophrenia and schizoaffective psychoses; and. 2. valproate augmentation of antipsychotic medication is an effective treatment for the same illnesses. Search strategy
  2. Depakote is not an approved medication for schizophrenia; it's a mood stabilizer used to treat bipolar disorder and/or acute mania. It works to balance depression and mania so a person won't experience extreme mood fluctuations. A 2014 study fou..
  3. Side Effects of Antipsychotics While the first-generation, older meds usually cost less, they can have different side effects than the newer antipsychotics. Some can cause higher levels of the.
  4. Depakote side effects. Get emergency medical help if you have signs of an allergic reaction to Depakote (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling)
  5. g very ill with the lower dosage. I became irritable. I couldn't calm me down enough to do something or to even watch a tv. I became very depressive and anxious too. I came back on the proper dosage now again. But i felt so bad without the Depakote that its strange for me that i need it so much
  6. To reduce side effects, the doctor probably will prescribe a low dose of Depakote to start and increase it slowly. Children usually start with a dose of 5 to 10 milligrams (mg) for each kilogram (kg, about 2.2 pounds) of their body weight per day
  7. Patients (n =249) who met DSM-IV criteria for schizophrenia were randomly assigned to receive olanzapine monotherapy, risperidone monotherapy, divalproex plus olanzapine, or divalproex plus..

Depakote Dosage Guide - Drugs

Depakote (divalproex sodium) dosing, indications

Dosage The dosage of Depakote can vary greatly, and as such, you should only take the dosage prescribed by your physician. Many considerations are taken into account when deciding dosage. Some of these are diagnosed condition, weight, previous medications, and response to therapies Abilify (aripiprazole) is a prescription drug used to treat mood disorders such as schizophrenia. Learn about side effects, warnings, dosage, and more. (Depakote) lamotrigine (Lamictal The purpose of this study is to examine the safety and efficacy of Depakote ER in bipolar depression and to evaluate metabolic and GABA changes with Depakote ER administration using PET and MRI/MRS brain imaging techniques. Mood disorders are important public health problems. Bipolar disorder is a major psychiatric disorder characterized by. Schizophrenia.com. Still cycling on 500mg Poll. DX'd - Other. Wave. June 3, 2021, 9:03pm #1. Deep lows today. Self harm images. I really don't want to increase my Depakote dose to 1000mg but my current dose of 500mg is not cutting it

A review of Valproate (Depakote) as a - schizophrenia

Divalproex sodium occurs as a white powder with a characteristic odor. Depakote tablets are for oral administration. Depakote tablets are supplied in three dosage strengths containing divalproex sodium equivalent to 125 mg, 250 mg, or 500 mg of valproic acid Depakote —> can result in biotin deficiency and low biotinidase enzyme activity —> results in alopecia (hair loss). Additional role of low zinc level with long term depakote treatment. The following study supports this underlying mechanism: 32 pediatric patients (22 females, 10 males) receiving valproate treatment

Valproate (Depakote) NAMI: National Alliance on Mental

Valproate for schizophrenia - PubMe

  1. valproate is the molecule that ends up in your bloodstream, but taken by itself it can cause stomach upset often. divalproex is a pair of forms of valproate which used together cause much less stomach upset. divalproex is now available as a generic, so let's drop the term Depakote , the former trade name, except to know the following:
  2. I usually only write plasma levels outside of Lithium/Depakote/Clozaril if I'm seeing zero side effects and zero benefit at a high dose, for example, I had one patient on 30mg of Haldol and literally zero side effects. Turns out, she was a rapid metabolizer and I ended up having to get her off the medication
  3. al misdemeanor for misbranding Depakote in violation of the Federal Food, Drug and Cosmetic Act (FDCA). Abbott's cri
  4. The delayed-release tablets are also used to control the manic episodes--periods of abnormally high spirits and energy--that occur in bipolar disorder (manic depression). An extended-release form of this drug, Depakote ER, is prescribed to prevent migraine headaches. The delayed-release tablets are also used for this purpose
  5. Depakote, which is generically known as Valporic Acid, is a drug used to treat migraines and schizophrenia. It is an anti-convulsant or mood-stabilizer. It is manufactured by Abbott Laboratories for the United States markets and is sold under alternate names like Depakene and Epival. Valporic acid was discovered over 100 years ago, but it was.
  6. Depakote is a commonly marketed name for valproic acid. This acidic chemical compound is used as a mood stabilizing and anticonvulsant drug, which treats bipolar disorder, epilepsy, depression, migraines, and schizophrenia. The drug was first synthesized in 1882 as an analogue of valeric acid, which is naturally found in valerian. The drug was approved asRead Mor

Schizophrenia and valproate - PubMe

  1. Two-mg/day and 6- to 16-mg/day doses of risperidone were compared with a 20-mg/day dose of haloperidol. The 2-mg/day dose of risperidone had approximately the same effect on positive symptoms of schizophrenia as the 20-mg/day dose of haloperidol (Figure 3). The severity of positive symptoms improved similarly in the 2-mg/day risperidone-treated.
  2. Not traditionally, no. Though you could consider valproate's blocking of voltage-gated sodium channels to be a depressant effect, as it reduces neurotransmission, anticonvulsants such as sodium valproate (aka Depakote) are not traditionally groupe..
  3. In the agreed statement of facts, Abbott also admitted that from 2001 through 2006, the Company misbranded Depakote by marketing the drug to treat schizophrenia. Abbott funded two studies of the use of Depakote to treat schizophrenia, and both failed to meet the main goals established for the study
  4. 52-week, multiphase study evaluated the time to relapse for adult patients with schizophrenia diagnosed ≥3 years with a history of symptom exacerbation or relapse when not receiving antipsychotic treatment (DSM-IV-TR criteria) 3‡. Open-label Phase 1: Patients were converted to oral aripiprazole. Open-label Phase 2: Patients were stabilized.

Agins, Alan P. ADA Quick Guide to Drug-Supplement Interactions, 2011. BioMed Research International : Characterization of schizophrenia adverse interactions through a network approach and drug. Divalproex, formally know as divalproex sodium and more commonly known by its brand name Depakote®, was first approved by the United States Food and Drug Administration (FDA) in 1983 for the treatment of epilepsy. More recently, on May 10th 2006, the United States Food and Drug Administration (FDA) approved safety labeling revisions to advise of the risk for fetal harm associated with use of.

Video: Seroquel vs. Depakote for Schizophrenia, Bipolar Disorder ..

Valproate for schizophrenia Cochran

CAPLYTA (lumateperone) package insert ( PDF) Lieberman JA, Davis RE, Correll CU, Goff DC, Kane JM, Tamminga CA, Mates S, Vanover KE. ITI-007 for the Treatment of Schizophrenia: A 4-Week Randomized, Double-Blind, Controlled Trial. Biol Psychiatry. 2016 Jun 15;79 (12):952-61. ( pubmed Too bad about the side effects- it's always a trade off. I believe in limited/lowest dose possible use of medications with a strong management plan. I would not be alive without the judicious use of medications. Trying to treat bipolar disorder, schizoaffective and schizophrenia without some kind of medication help is nigh on impossible

1. Schizophrenia, Anxiety, Bad Thought. Throwing up, diarrhea, moodswings, thoughts of suicide and memory loss, it also gave me hearing problems. It made my brain burn there are damaged nerves in my brain i can't listen to music like I used to my brain gets sore now because of the depakote I took it three years ago Depakote is the brand name for divalproex sodium, an anti-seizure medication given for those suffering from epilespy, other conditions that cause seizures, migraines and the manic phase in bipolar disorder. It's also often prescribed for schizophrenia and recovery from drug addiction, but those are off-label uses For migraine prevention, the recommended starting Depakote dosage is 250 mg twice a day. This eMedTV segment also provides Depakote dosing recommendations for the treatment of epilepsy and manic episodes associated with bipolar disorder

Depakote Class Action Lawsuits and Lawyers. Depakote is an anticonvulsant drug manufactured and marketed by Abbott Laboratories. This drug has been used for nearly 25 years to treat individuals suffering from epilepsy, manic bipolar behavior, and migraines. In recent years, however, class action lawsuits have been filed against Abbott. Haloperidol. The recommended oral dose for schizophrenia is 0.5-5 mg two or three times daily up to a maximum dose of 30 mg daily. The lactate solution dose is 2-5 mg every 4-8 hours as needed by intramuscular injection. The lactate solution may also be administered by intravenous injection at 1-2 mg every 2-4 hours and titrated to effect Depakote is an anti-seizure and mood-stabilizing drug prescribed for bipolar disorder. However, the company admitted that it marketed the drug for unapproved uses, including treatment of schizophrenia, agitated dementia and autism May 2012 - Abbott agrees to pay $3 million to the state of Arkansas to settle claims that the drug company marketed Depakote for unapproved uses, including autism and schizophrenia. May 2012 - Abbott Laboratories is ordered to pay $1.6 billion in fines to resolve charges that the drug maker illegally marketed Depakote for off-label uses.

How is Depakote used to treat schizophrenia? - Quor

DOSAGE AND ADMINISTRATION 2.1 Schizophrenia . The recommended starting dose of LATUDA is 40 mg once daily. Initial dose titration is not required. LATUDA has been shown to be effective in a dose range of 40 mg per day to 160 mg per day [see Clinical Studies (14.1)]. The maximum recommended dose is 160 mg per day Abbott pleaded guilty to misbranding Depakote by promoting the drug to control agitation and aggression in patients with elderly dementia and to treat schizophrenia when neither use was approved. Depakote (Divalproex Sodium) received an overall rating of 5 out of 10 stars from 4 reviews. See what others have said about Depakote (Divalproex Sodium), including the effectiveness, ease of use and side effects Find everything you need to know about Depakote (divalproex sodium), including what it is used for, warnings, reviews, side effects, and interactions. Learn more about Depakote (divalproex sodium.

Medications Used To Treat Schizophrenia - WebM

  1. Quetiapine Dosage for Schizophrenia For individuals age 13 years and older, the recommended starting dose of quetiapine for schizophrenia is 25 mg, taken twice a day. Generally, your healthcare provider will increase your dose quickly within a few days, up to 800 mg (taken in two or three smaller doses per day), if needed
  2. The usual oral dose of olanzapine for treating schizophrenia is 10-20 mg once daily. Therapy is initiated with 5-10 mg/day, and the dose may be increased by 5 mg a day at weekly intervals. The maximum dose is 20 mg daily. The recommended dose of extended release injection is 150-405 mg every 2 or 4 weeks
  3. Depakote (divalproex) is good for long-term prevention of seizures, manic episodes in bipolar disorder, and migraines. Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics
  4. Doctors prescribe antipsychotics such as Depakote, Risperdal, Abilify, and Zyprexa to people with schizophrenia, schizoaffective disorder, bipolar disorder, mania, and other psychoses. These drugs have many side effects that are unwelcome. 22 Some antipsychotic side effects make mental conditions worse and sometimes the drug itself makes mental.

The Justice Department said in a release that the company illegally marketed Depakote for off-label uses, or those not approved by the FDA, including for treatment of schizophrenia, agitated. Terminology. Valproic acid (VPA) is an organic weak acid.The conjugate base is valproate. The sodium salt of the acid is sodium valproate and a coordination complex of the two is known as valproate semisodium.. Medical uses. It is used primarily to treat epilepsy and bipolar disorder.It is also used to prevent migraine headaches.. Epilepsy. Valproate has a broad spectrum of anticonvulsant. Q. My wife has tardive dyskinesia (TD) from taking Zyprexa years ago for bipolar disorder. In April 2019, she began taking Austedo for the involuntary movements. Her neurologist helped get a grant.

Prolixin,1.5mg.twice per day dosing (was just increased but not sure of new dosage) Depakote, 500mg, twice per day dosing Cogentin,1.5 mg, In case of schizophrenia, dose of medications depend upon symptoms. As you have told that your son has had schizophrenia for last 10 years, so in his case, due to tolerance, increase in dose of. Valproic acid (Depakote) is an antiseizure medication. It is used to treat schizoaffective disorder, panic disorder, some dissociative disorders, borderline personality disorder, and to assist in withdrawal from the minor tranquilizers, such as Valium and Xanax, among others. Risks and Side Effects of Valproic Aci 1. Introduction. The prevalence and severity of psychiatric disorders are well substantiated by epidemiologic data, where an estimated 26-30% of the U.S. population is affected by at least one mental illness annually (Kessler et al., 1994; Kessler et al., 2005).Compounding this issue, psychotropic medications have had limited treatment success owing to delayed onset of therapeutic activity. Maximum recommended dosage is 60 mg/kg/day PO. If total dose > 250 mg/day, give in divided doses. Acute mania or bipolar disorder: Initially, 25 mg/kg/day PO once daily. Dose should be increased rapidly to achieve the lowest therapeutic dose. Maximum dose 60 mg/kg/day PO (Depakote ER only)

In May, 2012, Abbott Labs agreed to a $1.6 billion settlement of federal and state claims that it marketed Depakote for unapproved, off-label use. Although Depakote was never approved for treatment of schizophrenia, dementia and autism, Abbott created and trained a sales force specifically to target nursing directors, geriatric doctors and. My wife has been on Depakote/Epival for much of her adult life. For her, it worked relatively well with minimum noticable side effects. She didn't experience much issues with weight gain and sedation, though it should be noted that her dosage amount has typically been on the lower end of the therapeutic range (500-1000mg) Schizophrenia affects 1 percent of the population. Depakote, Lamictal, Tegretol, The medical version of the ketogenic diet has risks and side effects. You should have accurate information. depakote is given for several reasons. i give it in the alzheimer patients for aggressive behavior but, others ive given it for seizures. seroquel is used in the population i work with (alzheimers,dementia) for agressive behavior as well. truthfully i dont think i ever given seroquel for it intended use,meaning schizophrenia. when we start seroquel ,it is started ususally at 25mg once or twice.

Yeah we've played around with the timing of the doses also. anywhere from 1-2 hours before. Doesn't seem to make much of a difference. Her depakote should be at therapeutic dose. SHe got her blood work done when taking 750mg and her psychiatrist said it came back fine HI, I was recently put on 750 mg of Depakote ER. I have looked far and wide on the internet and have found only a little info about this drug being used for PTSD. I know it is mainly used for seizures and bipolar (which I do not have). I was curious if anyone else has taken Depakote ER for.. The recommended target dose of ABILIFY is 10 mg/day. Aripiprazole was studied in adolescent patients 13 to 17 years of age with schizophrenia at daily doses of 10 mg and 30 mg. The starting daily dose of the tablet formulation in these patients was 2 mg, which was titrated to 5 mg after 2 days and to the target dose of 10 mg after 2 additional. Depakote ER, mean daily dose of 1457.2 + 532.9 mg/day (range 750-3250mg) with average plasma concentration of 27.1 + 6.3 mg/kg/day was achieved in the Depakote ER group 2 DOSAGE AND ADMINISTRATION 2.1 Schizophrenia 2.2 Depressive Episodes Associated with Bipolar I Disorder 2.3 Administration Information 2.4 Dose Modifications for Renal Impairment 2.5 Dose Modifications for Hepatic Impairment 2.6 Dose Modifications Due to Drug Interactions of CYP3A4 Inhibitors and CYP3A4 Inducers 3 DOSAGE FORMS AND STRENGTH

Shortness of breath and/or wheezing. Difficulty swallowing ( dysphagia ) Swelling in the face, throat, neck, or extremities. High fever (over 100.4 F) Serious side effects of Invega Sustenna and Invega Trinza are also uncommon but may include: 1 . Seizures, tics, tremors, or convulsions In 2012, Depakote received attention for its slew of dangerous side effects. The U.S. Department of Justice and 45 states sued the makers of Depakote for promoting the drug for dementia and schizophrenia, two uses unapproved by the FDA. Because of widespread illegal marketing, manufacturers of Depakote became the target of a class-action lawsuit

The psychiatrist at the hospital had now increased his dosage of Geodon and added Depakote. When I spoke to the nurse, she said that the Depakote was being used as a mood stabilizer. As for whether he schizophrenia or bipolar only a psychiatrist can make a diagnosis. But much more common than schizophrenia is schizoaffective which is. Depakote is FDA-approved for treatment of seizure disorders, symptoms of manic depression and the prevention of migraines. The states allege Abbott defrauded the Medicaid program and engaged in unfair and deceptive practices when it marketed Depakote for off-label uses, such as for the treatment of schizophrenia, agitated dementia and autism

Depakote: Drug Uses, Dosage & Side Effects - Drugs

Depakote is for seizures, mania or migraines. Image from StockXChng. Depakote is the brand name for divalproex sodium, an anti-seizure medication given for those suffering from epilespy, other conditions that cause seizures, migraines and the manic phase in bipolar disorder. It's also often prescribed for schizophrenia and recovery from drug addiction, but those are off-label.Read More.. Abbott was marketing its anti-seizure drug Depakote off-label uses for schizophrenia and even migraines. Now they owe the US government $700 million dollars, as a federal judge approved a $1.6 billion settlement between the manufacturer and the U.S. Department of Justice Olanzapine oral tablet is a prescription drug used to treat schizophrenia, depression, and bipolar I disorder. It comes as a regular tablet and an orally disintegrating tablet. It's available in.

Depakote is effective for many patients and is an important treatment for seizure disorders, but there are possible side effects too. Most commonly it causes drowsiness and dizziness, weight gain, nausea, and diarrhea. Rarely, it may cause excessive bruising, hair loss, liver damage, disorientation, confusion, and other cognitive difficulties Reviewer: 55-64 Female on Treatment for 10 years or more (Patient) Effectiveness. Current Rating: 5. Ease of Use. Current Rating: 5. Satisfaction. Current Rating: 4. Comment: Have been on Depakote oral dose for over 25yrs Depakote (divalproex) is listed as possibly interacting, but she was not warned by either her neurologist or the pharmacy. Answer: Antipsychotic drugs such as olanzapine (Zyprexa) are prescribed for schizophrenia, bipolar disorder and major depression Side Effects: Neutropenia when used in conjunction with Clozapine (Malik, 2018) Clozapine is the only evidence based medication in treating treatment resistant schizophrenia which affects about ⅓ of patients with schizophrenia Schizophrenia Medications. Pfizer sent letters to physicians yesterday to notify them that its schizophrenia drug Geodon might cause coma and death. Pfizer has added a warning to the Geodon label stating that some patients have experienced hyperglycemia after using the drug. Patients with diabetes risk-factors, such as obesity or family history.

Vraylar ® (cariprazine) is a once-daily, oral, atypical antipsychotic drug indicated for the treatment of adults with bipolar I disorder and schizophrenia, discovered and co-developed by Gedeon Richter and licenced to Allergan in the US and Canada.. The drug was approved by the US Food and Drug Administration (FDA) in September 2015 for the acute treatment of manic or mixed episodes. 2.2 Schizophrenia The recommended dosage range is 1.5 mg to 6 mg once daily. The starting dosage of VRAYLAR is 1.5 mg daily. The dosage can be increased to 3 mg on Day 2. Depending upon clinical response and tolerability, further dose adjustments can be made in 1.5 mg or 3 mg increments. The maximum recommended dosage Long-acting injectable (LAI) antipsychotics are a pharmacologic strategy for treating patients with schizophrenia who relapse due to nonadherence to antipsychotic medication. Rather than the daily pill-taking required with oral antipsychotics, LAI antipsychotics are administered by injection at two- to four-week intervals

Olanzapine (Zyprexa) is one of a group of newer antipsychotic medications called atypical antipsychotics. These types of medication are seen as a better choice for people with Alzheimer's than other older antipsychotic medications. However, Zyprexa is not approved by the US Food and Drug Administration for the treatment of psychosis in older. The pharmaceutical giant has agreed to $1.6 billion in criminal and civil fines for illegally promoting unapproved uses of the drug Depakote Negative symptoms of schizophrenia are those involving the absence of something common to most healthy people. This can include lack of communication, social interaction, and motivation

Who is on depakote? Whats his effects - Schizophrenia

Depakote. Depakote is a brand name for a drug called valproate semisodium, which is also called divalproex sodium or valproic acid. The medication is used to treat seizure disorders such as epilepsy. The medication is also prescribed to prevent migraine headaches. Depakote was first approved for the treatment of epilepsy in 1983 and was. Depakote is approved for treatment of seizure disorders, mania associated with bipolar disorder and prophylaxis of migraines, but Attorney General Schneiderman alleged that Abbott marketed the drug for treating unapproved uses, including schizophrenia, agitated dementia and autism

Divalproex Sodium Epilepsy Foundatio

Effect of Divalproex Combined with Olanzapine or

For schizophrenia the starting dose is asenapine 5 mg twice daily. For monotherapy in bipolar disorder the starting dose is asenapine 10 mg twice daily, and for combination therapy with lithium or valproate the starting dose is asenapine 5 mg twice daily. The dose can be adjusted in the range 5 mg to 10 mg twice daily after clinical assessment Benztropine is used along with other medications to treat the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) and tremors caused by other medical problems or medications. Benztropine is in a class of medications called anticholinergics

Depakote (Divalproex Sodium) - Side Effects, Interactions

Depakote for Bipolar Disorder: Facts, Side Effects, Cost

QUESTION: My wife has tardive dyskinesia from taking Zyprexa years ago for bipolar disorder. In April 2019, she began taking Austedo for the involuntary movements. Her neurologist helped get a. Dosage. For schizophrenia, the recommended initial dose is 25 mg two times a day. The dosage is increased to 300 to 400 mg a day Depakote . The brand name for sodium divalproex, which is an anticonvulsant, is Depakote.It consist of sodium valproate and valproic acid. It is used to treat several conditions such as epilepsy, migraines, mania. Olanzapine (Zyprexa, Zyprexa Zydis) is a moderately priced drug used to treat schizophrenia, psychotic disorders, and bipolar disorder.It is slightly more popular than comparable drugs. It is available in multiple generic and brand versions. Generic olanzapine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower Initially, Seroquel seemed to have few side effects or complications, making it appealing as an alternative to the highly addictive benzodiazepines approved for insomnia and anxiety, among other. The psychiatrist at the hospital had now increased his dosage of Geodon and added Depakote. When I spoke to the nurse, she said that the Depakote was being used as a mood stabilizer. Is Depakote used for anger management? Read More. hello, i am diagnosed with schizophrenia and am on 4 medications: lamictal, invega, geodon and wellbutrin. my.

Depakote ER FULL Prescribing Information PDR

Nevertheless, Abbott Labs trained a special sales team to promote Depakote in nursing homes for treatment of certain symptoms of elderly dementia and then later for treatment of schizophrenia. The company's research into the use of Depokote to treat elderly dementia had been halted very early on after the drug showed severe side effects. The company also marketed Depakote to treat schizophrenia. Clinical trials failed to demonstrate that adding Depakote was any more effective than antipsychotic drugs in treating schizophrenia.

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